Creatine Monohydrate CAS: 6020-87-7

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Creatine monohydrate is a naturally occurring nitrogen-containing organic acid that serves as a nutritional fortifier and a versatile fine chemical raw material for the food and industrial sectors. It is widely used in industries such as sports nutrition and health supplements, functional foods and beverages, pharmaceutical and nutraceutical raw materials, animal feed and aquaculture, pet food and animal health, and cosmetics and personal care. Safe, non-toxic, highly compliant, and stable, it is a nutritional chemical raw material with broad global applicability.

Creatine monohydrate is a raw material widely used across various industries. Its specific end use depends on factors such as mesh size, stability, and purity. The following section outlines its primary applications based on buyer requirements.

Sports Nutrition and Health Supplements

This is the largest application sector for creatine monohydrate. For buyers and manufacturers, mesh size directly affects solubility and the characteristics of downstream products. Finer grades, such as 200-mesh creatine monohydrate, dissolve more easily in water and are typically used in instant or easy-mix powder products. By contrast, coarser grades, such as 80-mesh creatine monohydrate, offer superior flowability and tableting properties, making them ideal for capsule and tablet production.

The production of creatine monohydrate generates two by-products, dicyandiamide (DCD) and dihydrotriazine (DHT), which directly affect product purity and the quality of downstream goods. Therefore, beyond simply focusing on purity levels, it is essential to monitor DCD and DHT content.

Please refer to our Certificate of Analysis (COA), which details all critical parameters, including DCD and DHT levels, so you can quickly understand product quality and make informed purchasing decisions.

Functional Foods and Beverages

Regulations governing the use of creatine as a food ingredient vary by country. In China, creatine monohydrate is listed under the GB 14880 standard for use as a nutritional fortifier in specific food categories. In the European Union and the United States, it is typically classified as a food or dietary supplement, with maximum usage limits established for different categories. Buyers should verify the applicable standards and permitted limits for their target markets before procurement.

Pharmaceutical and Nutraceutical Raw Materials

In the pharmaceutical and health supplement industries, creatine monohydrate is mainly used as a raw material for nutritional formulations that support muscle metabolism and for clinical nutrition products. Therefore, when used as a raw material, it must comply with pharmacopeial standards such as USP. In addition to meeting purity requirements, comprehensive documentation detailing the manufacturing process and impurity levels must be provided. Similar to applications in sports nutrition, mesh size and powder flowability are critical for tablet, capsule, and sachet production. Buyers in this sector often request additional data on flowability and bulk density alongside the standard Certificate of Analysis (COA).

Animal Feed and Aquaculture

In feed for aquaculture, livestock, and poultry, the addition of appropriate amounts of creatine monohydrate supports cellular energy metabolism and muscle development. In certain formulations, it also helps mitigate the physiological effects of heat stress or transport stress associated with large-scale intensive farming.

Creatine degrades under the high-temperature and high-pressure conditions typical of pelleting and extrusion processes. Consequently, this sector has specific requirements regarding thermal stability. Buyers should provide production-line-specific stability data based on their manufacturing processes and requirements so that performance specifications for the creatine monohydrate raw material can be defined and appropriate solutions developed.

Pet Food and Animal Health

Much like its role in human nutritional supplements, creatine added to pet food formulations for working, athletic, and senior dogs supports muscle energy metabolism and helps maintain a stable, healthy body weight.

As pet food is predominantly produced in pellet form, often using extrusion technology, thermal stability requirements apply here just as they do for livestock feed. We can provide guidance on creatine's thermal stability at specific extrusion temperatures tailored to your production needs.

Cosmetics and Personal Care

Creatine is frequently used in anti-aging and firming formulations, such as serums and creams. Inclusion levels depend on the specific formulation; historically, usage rates have been relatively low, typically ranging from 0.1% to 3%.

Buyers in this sector usually require product specifications that comply with cosmetic regulatory frameworks, such as EU Cosmetic Regulation limits for heavy metals and microorganisms, rather than standard food-grade or pharmaceutical-grade benchmarks. Please contact us for relevant documentation or to discuss customized solutions if you have specific requirements regarding mesh size.

Creatine monohydrate is typically produced industrially through chemical synthesis. Using sarcosine and cyanamide as raw materials, the synthesis reaction is carried out under specific conditions, followed by decolorization, purification, crystallization, centrifugation, drying, and screening to obtain the final product. Finished products can be processed to meet specific purity and particle size (mesh) requirements based on downstream production needs.

Every batch of creatine monohydrate supplied by Sinoright undergoes rigorous quality review to ensure raw material traceability and batch-to-batch consistency. Precise control is maintained at critical stages of the manufacturing process to eliminate harmful impurities such as DCD and DHT and ensure exceptionally high product purity (≥99.5%). In addition to providing a Certificate of Analysis (COA), we can arrange independent pre-shipment sampling and testing by certified third-party laboratories to verify key parameters, including purity, moisture content, and heavy metal limits. We also oversee the final packaging and loading processes to ensure the cargo remains protected from moisture contamination during transit.

Stable bulk supply – Direct sourcing from top Chinese manufacturers at factory prices

Thanks to our large-scale production capacity and robust supply chain system, we maintain ample inventory of creatine monohydrate. We have also established a highly responsive supply chain network.

 

This enables us to monitor market price fluctuations for this product and its upstream and downstream materials in real time. While ensuring uninterrupted supply, we can develop the most cost-effective procurement strategy for you, helping you optimize purchasing decisions in a changing market.

High-quality products – Strict quality control ensures high purity and low levels of harmful impurities

We supply high-quality products with exceptional purity. Purity of our creatine monohydrate is more than 99.5% with low levels of DCD (≤50ppm), catering to diverse applications for commercial supplement brands and manufacturers, including dietary supplements, functional food and beverage, pharmaceutical raw materials, personal care, and so on.

 

We guarantee high-quality products backed by an ISO 9001-certified quality management system. Every shipment comes with full documentation, including a Certificate of Analysis (COA), and supports third-party testing. Should any quality issues arise, we are committed to providing a satisfactory solution.

One-stop service – Professional support for multi-product FCL consolidation

We offer flexible payment terms, including T/T, L/C, D/P, D/A, O/A, and Alipay. As a one-stop solutions provider, we offer professional services covering every stage of the process, from solution recommendations and logistics booking to hazardous materials declarations, multi-product FCL consolidation, door-to-door transportation, and customs clearance assistance at the destination port, helping resolve any issues that may arise along the way.

 

So if you need to purchase a mix of products in one order-such as other food additives-just let us know what you're looking for. We offer flexible consolidated shipping (LCL) to help you save on freight costs and simplify your sourcing process. If you require ODM (private label) services, we can put your brand on the packaging, making it easy for you to launch your own branded products.

Professional market insight – A professional sales team shares market trends and price forecasts

We have assembled a dedicated team of technical experts, sales professionals, and customer service specialists to provide 24/7 support. We offer expert guidance on the transportation, handling, and storage of creatine monohydrate, as well as assistance with any technical issues encountered during production and application.

 

If you would like to stay informed about the latest developments and industry analysis in China's creatine monohydrate market and the fine chemical sector, you are welcome to consult our senior sales colleagues at any time for authoritative market analysis reports and industry insights. Let us serve as your dedicated R&D and procurement department in China.

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